Losartan + Hydrochlorothiazide tablets Uses, Side Effects, Dose, Price, Brand

Losartan + Hydrochlorothiazide tablets Uses, Side Effects, Dose, Price, Brand


This medicine is prescribed for the treatment of hypertension, effectively lowering blood pressure levels. It also helps to reduce the risk of stroke in people who have high blood pressure and heart hypertrophy. Lowering high blood pressure contributes greatly to the prevention of strokes, heart attacks, and renal problems.

This medication contains two active ingredients: losartan and hydrochlorothiazide. Losartan, classified as an angiotensin receptor blocker (ARB), works by relaxing blood arteries, allowing for better blood circulation. As a diuretic or “water pill,” hydrochlorothiazide promotes increased urine output by increasing diuresis. This diuretic effect helps the body eliminate extra salt and water.

How to Use Losartan / hydrochlorothiazide

Administration Guidelines:

Usage: Take this drug orally as directed by your healthcare practitioner, usually once day. Consumption can occur either with or without food.

Managing urine Frequency: If this drug causes more urine, it is best to take it at least 4 hours before bedtime to avoid nighttime urinating.

Interaction with Cholesterol-Lowering Drugs: If you are taking specific cholesterol-lowering medications at the same time, such as bile acid-binding resins (e.g., cholestyramine or colestipol), wait at least 4 hours before or 4 to 6 hours after you take losartan/hydrochlorothiazide.

To reap the most benefits from this drug, make sure you take it on a regular basis. Establish a regular intake routine, sticking to the same time each day. Maintain the course of this medication even if there are no visible indications of sickness, as people with high blood pressure are frequently asymptomatic.

Please notify your healthcare provider as soon as possible if your situation does not improve or worsens, such as an increase in your blood pressure readings.

Dosage Calculation: The advised dosage is determined by your medical condition and reaction to treatment.

Side Effects

As your body adjusts to the medicine, you may experience dizziness or lightheadedness. If any of these adverse effects persist or worsen, you must immediately contact your healthcare professional or pharmacist.Exercise caution and gradually rise from a seated or recumbent posture to reduce the probability of dizziness and lightheadedness.

It is critical to remember that this medication was prescribed by your healthcare professional because the benefit to you outweighs the risks of probable side effects. A considerable majority of people who use this medicine do not have serious side effects.

This product can cause dehydration and electrolyte imbalances. Notify your doctor right away if you have any of the following signs of dehydration or electrolyte imbalance: excessive thirst, excessively dry mouth, muscle cramps or weakness, irregular heartbeat (either rapid or slow), or confusion.

If you experience any severe side effects, notify your healthcare provider immediately, including but not limited to: fainting episodes, decreased vision, ocular discomfort, signs of elevated blood potassium levels (e.g., muscle weakness, irregular or slowed heartbeat), or signs of renal issues (e.g., changes in urine volume).

While a severe allergic reaction to this medication is rare, get emergency medical assistance if you notice symptoms of a severe allergic reaction, such as a rash, pruritus, swelling (especially of the face, tongue, or neck), severe vertigo, or respiratory problems.

Please keep in mind that the above list does not include all possible negative effects. Please notify your healthcare professional or pharmacist as soon as possible if you notice any additional adverse effects not included in the preceding list.


Please contact your healthcare professional or pharmacist if you have ever had an allergic reaction to losartan or hydrochlorothiazide, or if you have any additional allergies. This product may include inactive ingredients that could cause allergic reactions or other issues. Consult your pharmacist for more information.

In preparation for starting this drug, tell your healthcare professional or pharmacist about your medical history, especially if you have a history of gout, kidney or liver diseases, lupus, dehydration, increased potassium levels in the blood, or skin cancer.

It is critical to recognize that this medication can cause dizziness. The use of alcohol or marijuana (cannabis) might aggravate dizziness. Refrain from using machinery, driving, or engaging in activities that demand increased awareness until you can do so safely. If you use marijuana (cannabis), use caution with alcoholic beverages and see your doctor.

Inform your healthcare practitioner if you are pregnant or planning to get pregnant. It is critical to avoid pregnancy when using this product. Losartan has the potential to harm an unborn child. If you become pregnant, talk to your doctor right away about the risks and benefits of this drug (for more information, see the Warning section).

Losartan’s absorption into breast milk is unknown. Although hydrochlorothiazide passes into breast milk, it is unlikely to damage a breastfeeding infant. Consult your doctor or pharmacist before beginning to breastfeed.

Brand name

  1. Hyzaar

Pakistani Brand & Price

  • Xeta Plus tablets 50mg/12.5mg (PKR 150)
  • Co-Eziday tablets 50mg/12.5mg (PKR 335)
  • Corik-H Tablets 50mg/12.5mg (PKR 45)
  • Co-eziday 100/25mg (PKR 215)
  • Xavor DIU 50/12.5mg (PKR 163)
  • Sarcol-H 50/12.5mg (PKR 215)
  • Rosar-H tablets 50/12.5mg (PKR 276
  • Qusartan plus tablets 50/12.5mg


Drug interactions can reduce the efficacy of your treatments or increase the risk of severe side effects. It is crucial to remember that this paper does not cover the entire range of potential medication interactions. Keep a detailed record of all products you use, including prescription and nonprescription pharmaceuticals, as well as herbal supplements, and share this list with your doctor and pharmacist. Do not start, stop, or change the dosage of any medications without first consulting with your doctor.

Certain drugs, such as aliskiren, dofetilide, lithium, and medications that may raise potassium levels in the system (e.g., sparsentan, ACE inhibitors like benazepril/lisinopril, and drospirenone-containing contraceptives), may interact with this medication.

Disclaimer: All material offered is based on data gathered and personal experiences. Before beginning any medicine, it is strongly recommended that you consult with a licensed medical expert. Certain materials are used for educational purposes under the terms of fair use.

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