Prephenazine oral: Uses, Side Effects, How to Use, Warnings and More

Prephenazine oral: Uses, Side Effects, How to Use, Warnings and More

Perphenazine Uses

Specific mental and emotional illnesses such as schizophrenia, bipolar disorder’s manic phase, and schizoaffective disorder are treated with this medicine. This medication’s main goals are to improve mental clarity, reduce anxiety, and make it easier to participate in everyday activities. It also attempts to lessen violent impulses and the desire to hurt oneself or other people. Moreover, it might aid in the reduction of hallucinations, which are delusions characterized by false visual or aural impressions. Perphenazine is categorized as an antipsychotic psychiatric drug that works by helping the brain’s natural chemical balances—like dopamine—to once again be restored.

Perphenazine How to use

As per your doctor’s instructions, take this medication orally once or three times per day, with or without food. The recommended dose depends on your health and how well you respond to the medication. In order to reduce the possibility of adverse effects like muscular spasms, your doctor could first recommend a low dosage that is gradually increased. Follow your doctor’s instructions exactly.

Take this drug as prescribed to maximize its therapeutic advantages. Make sure you take it at the same time(s) every day to help with adherence.

Even though you could start to feel some results right away, it can take up to four or six weeks of consistent usage to get the full advantages. Avoid stopping this medicine suddenly without first talking to your doctor, since it might make your condition worse. Your doctor will walk you through a progressive dosage decrease procedure if stopping becomes required.

Perphenazine side effects

Drowsiness, constipation, dry mouth, dizziness, lightheadedness, blurred vision, fatigue, or unexplained weight gain are some of the possible side effects of this medicine. Please notify your pharmacist or doctor right away if any of these side effects worsen or continue.

When feeling lightheaded or dizzy, there is an increased chance of falling. When getting out of a sitting or supine posture, go cautiously and gently.

If you suffer any of the following: drooling, trouble swallowing, a mask-like look on your face, restlessness, shaking (tremor), muscular spasm or stiffness, or a shuffling walk, inform your doctor right away. Your doctor might suggest a different medication to help with these side effects.

It is critical to understand that a positive risk-benefit analysis is the basis for your doctor’s prescription of this drug. Those who use this drug are not likely to have serious negative effects.

Tardive dyskinesia is a possible side effect that might be permanent in some cases. If you notice any involuntary or repeated muscular movements—such as lip-smacking or puckering, tongue thrusting, biting, or finger or toe motions—notify your doctor right away.

Rarely, perphenazine may increase the body’s levels of prolactin, one particular endogenous hormone. This increase in prolactin levels in females might cause problems with conception, irregular menstrual periods, or unwanted breastfeeding. It may show up in men as decreased libido, an inability to produce sperm, or the growth of larger breasts. As soon as any of these symptoms appear, you should definitely let your doctor know.


Tell your doctor or pharmacist about any known allergies to perphenazine, other phenothiazines (such fluphenazine and chlorpromazine), or any other allergens before starting perphenazine. This product can have inactive chemicals that cause allergic reactions or other problems. For more specific information, speak with your pharmacist.

Before starting this medication, tell your doctor or pharmacist about all of your medical history. It is important to pay close attention to any history of bone marrow problems, serious head injuries, liver problems, Parkinson’s disease, a history of drug or alcohol abuse, low blood pressure, breathing issues (like asthma or emphysema), breast cancer, heart valve problems, seizures, a certain type of adrenal gland tumor (pheochromocytoma), restless legs syndrome, or seizures.


When using this medicine, older people with dementia are somewhat more likely to get serious, sometimes fatal side effects such as heart failure, a fast or irregular pulse, and pneumonia. It is important to remember that this drug is not approved for the treatment of behavioral problems linked to dementia. It is recommended to have a thorough conversation with the physician about the advantages and disadvantages of this drug. It would also be beneficial to investigate possibly safer and more effective alternative therapies for behavioral issues associated with dementia.


Don’t give this medicine to anyone else.

Throughout the duration of this medicine, have routine laboratory and/or medical examinations, such as a complete blood count, liver function tests, and eye exams. Make sure you show up for all of your arranged lab and medical visits. For further details, see your doctor..

If a dosage is missed, take it as soon as you remember it. But if the next dose is coming up soon, skip the missed one and go back to your usual dosage schedule. Do not take two doses to make up for one that you missed.

Keep this medicine out of the sun and moisture, and store it at room temperature. Keep it out of the restroom. All drugs should be kept out of children’s and pets’ reach.

Unless specifically directed to do so, avoid flushing drugs down the toilet or throwing them down the drain. When the product’s expiration date approaches or it is no longer needed, dispose of it properly. For advice on appropriate disposal techniques, speak with your pharmacist or get in touch with your neighborhood trash disposal business.

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