Dydrogesterone oral: Introduction, Mechanism of action, Clinical Uses, Indication, Dosage and Side Effects


now this is a steroid hormone especially used by the female. What is the mechanism of this drug?

Mechanism of action

There is a hormone in women which is called uterus. The lining of the uterus is the endometrium called the myometrium. There is a hormone that stabilizes it called progesterone. Now you have the progesterone that stabilizes the uterus. Dydrogsterone, which is a drug, is actually progesterone. What it does is healthy growth and normal shedding of the Uterus. This drug is used for stabilization and is absorbed through the GIT.

It is metabolized by dydrogesterone and its metabolites. And it is very useful medicine to maintain pregnancy.

Clinical uses

Some women have menstrual disorders, Some women are low in certain hormones, so when these hormones are low, they have a major problem of miscarriage and those women lose their pregnancy.

Miscarriage occurs, and some women who do not become pregnant have dysmenorrhea, which is very painful during menstruation.
This drug is used as a hormone in women

Indication and dosage

Uses drugs orally, you use drugs in recurrent miscarriages, 10mg bid until 12th week of pregnancy

Infertility due to luteal insufficiency, the drug used in doses of 10 to 20 mg starting on the first day of the second half of the menstrual cycle. And some women have dysmenorrhea, i.e. heavy menstrual cramps, 10 to 20 mg dose for 5 to 25 days.

Side Effects,

Some side effects may occur from using this medicine.

  • Nausea
  • Vomiting
  • Abdominal pain
  • Diarrhea
  • Dry Mouth
  • Indigestion
  • Rash
  • Itching
  • Hives
  • Cough
  • Breast pain
  • Depression

Remember take any of drugs from the such drugs should be prescribed only after consultation with your gynecologist, who can guide you completely.


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